NEW: Important Study Finds Formaldehyde Does Not Cause Cancer by Gene Mutation

January 10, 2018
Advertisement

Report originally published by NFDA

Recently, the Health and Human Services National Toxicology Program (NTP) announced the results of an important study, ruling out the possibility that formaldehyde exposure causes cancer due to the mutation of the gene Trp53.

You may read the full study here. 

This study is good news for funeral directors as it leads to a better understanding of how formaldehyde may cause cancer and how to avoid those exposures.

Advertisement

Previous studies had suggested an association between mutations in the Trp53 gene, which is a tumor suppressor and formaldehyde-induced cancers. The objective of this study was to evaluate the potential role of the Trp53 gene.

The study concluded that inhalation by mice of a maximum tolerated dose of formaldehyde did not cause an increased incidence of nasal tumors, leukemia, or lymphohematopoietic tumors in Trp53+ mice. Both mouse strains developed a variety of cell changes and tumors, but all were considered not a result of formaldehyde exposure. NPT concluded that the results of this short-term carcinogenicity study do not support a role for Trp53 in formaldehyde-induced neoplasia.

The American Chemistry Council described the study as “add[ing] to the scientific evidence that finds formaldehyde doesn’t cause cancer.”

Formaldehyde is among the most widely studied of all chemicals. Formaldehyde inhalation has been linked to nasal cancer and leukemia, including myeloid leukemia in funeral directors. In 2011, the NTP determined that formaldehyde exposure may cause cancer in humans and listed formaldehyde for the first time as a carcinogen on its 14th Report on Carcinogens.

Domestic and international government agencies and scientists supported by industry have continued to study formaldehyde, trying to figure out the mechanisms by which formaldehyde causes cancer and the risk associated with formaldehyde exposure.

EPA’s Integrated Risk Information System (IRIS) program has not yet issued a revised formaldehyde risk assessment, following the agency’s 2010 risk assessment that was intensely criticized by the National Academy of Sciences. Under the European Union Biocides Product Regulation, Germany is expected to issue an evaluation of the risks associated with formaldehyde use in embalming, but not until 2023.

CDFuneralNews

CDFuneralNews

ConnectingDirectors.com is the leading online daily publication for funeral professionals with a reader base of over 45,000 of the most elite and forward-thinking professionals in the profession. With ConnectingDirectors.com we have created a global community through an online platform allowing funeral professionals to Stay Current. Stay Informed and Stay Elite.
CDFuneralNews
Advertisement

You may be interested

Funeral Cribs Episode 5 – Sunset Memorial Park, Alabama
News
402 views
News
402 views

Funeral Cribs Episode 5 – Sunset Memorial Park, Alabama

CDFuneralNews - January 18, 2018

The Sunset Memorial Park Funeral Home has had one major goal in mind from the time it started until now,…

Blog Archives Decedent’s Final Tweets… And They are Heartbreaking
Humor
378 views
Humor
378 views

Blog Archives Decedent’s Final Tweets… And They are Heartbreaking

Justin Crowe - January 16, 2018

The digital age has created some fascinating unprecedented scenarios concerning legacy. Facebook chronicles our lives, so when my kids are…

5 Ways to Build Your Business
News
175 views
News
175 views

5 Ways to Build Your Business

CDFuneralNews - January 16, 2018

Ask a business in this industry what differentiates them from their competitor and the answer is usually “service.” But to…

Comments